目的:探索住院医师规范化培训时应用以问题为基础的教学法(Problem-Based Learning, PBL)的意义。方法:选择2022年7月~2024年6月在复旦大学附属闵行医院进行规范化培训的住陪学员86名,随机分为观察组(传统教学与PBL教学法相结合教学模式,43名)和对照组(传统教学方式,43名)。对比这两组规培学员出科时的理论和临床技能考核成绩。结果:观察组住培学员的出科理论成绩(88.86 ± 5.78分)高于对照组住培学员(83.59 ± 3.72分) (P P Objective: This paper aims to explore the significance of applying Problem Based Learning (PBL) in standardized training for resident physicians. Methods: A total of 86 resident trainees who underwent standardized training at Minhang Hospital affiliated with Fudan University from July 2022 to June 2024 were randomly divided into an observation group (43 participants using a combination of traditional and PBL teaching methods) and a control group (43 participants using traditional teaching methods). The theoretical and clinical skill assessment scores of these two groups of trainees at the time of graduation were compared. Results: The theoretical scores of the observation group’s resident trainees (88.86 ± 5.78) were higher than those of the control group’s resident trainees (83.59 ± 3.72) (P P < 0.05). Conclusions: The PBL teaching method is beneficial for improving the theoretical knowledge and problem-solving ability of resident trainees, and is of great significance in improving the quality of standardized training for resident physicians.