The Tonglu volcano-intrusive complex belongs to a calci-alkalic rock series. The geochemistry of major and minor elements in the rocks is characteristic of the differentiation and the evolution of the calci-alkalic series. The rare-earth distribution patterns in the rocks and minerals indicate that rhyolitic, rhyodacitic and quartz ttachyandesitic magmas responsible for the volcano-intrusive complex are comagmatic. The Rb-Sr isotopic relationship in the rocks suggests that the earliest volcanic activity in western Zhejiang may commence at Middle Jurassic. The magma responsible for the Tonglu volcano-intrusive complex originated from partil melting of the lower crust. The derivation of upper mantle material was introduced upwards through deep faults, which would accelerate partial melting of the lower crust.This magma seems to have been contaminated slightly by upper crustal material during the process of upward intrusion.