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Nutritional and Antioxidant Evaluation and Effect of Eggplant Consumption on Anthropometric and Hematologic Parameters in Wistar Rats
2024年
The aim of the present study was to evaluate the nutritional quality of green and purple eggplant, their antioxidant activity and their nutritional efficacy on Wistar rats. For nutritional quality, the parameters measured are dry matter, protein, lipid, ash, carbohydrate, iron, phosphorus, calcium, magnesium and energy content. For antioxidant activity, the parameters measured are 50% DDPH free radical inhibition concentration and total polyphenol content. Nutritional efficacy was evaluated in rats fed the control diet and in rats fed the three treated diets containing eggplant meal obtained by replacing 5%, 10%, and 15% of the control diet. The parameters measured are the amount consumed, the weight of the animal and target organs, and hematologic parameters. The results of the nutritional analysis show the following values: 13.31% protein, 2.66% lipids, 0.84% calcium, 0.12% magnesium, 0.43% phosphorus for the Solanum aethiopicum L. species and 13.47% protein, 3.66% lipids, 0.36% calcium, 0.22% magnesium, 0.35% phosphorus for the Solanum melongena L. species. In terms of antioxidant activity, we obtained DDPH inhibition percentages of 40.28 mg/ml for Solanum aethiopicum L. and 12.42 mg/ml for Solanum melongena L., respectively. Finally, hematologic and anthropometric tests showed that for the different diets used, weight loss and an increase in hematologic parameters were observed in the rats tested. This study showed that eggplant has interesting nutritional characteristics and antioxidant activity, contributing to an increase in weight and anthropometric parameters.
Elenga MichelNkouka RhodeGouollaly TsibaWossolo StephaneItoua Okouango Yvon SimpliceMananga Vital
关键词:EGGPLANTANTIOXIDANTSPOLYPHENOLS
人因导向户外测量舱映射分析与设计应用
2024年
为解决大样本户外人体数据测量载平台设计局限所导致的测量效率低、测量成本高、人员设备安全性和适应性差等问题,文中进行人因导向户外测量舱的映射分析、设计与应用。基于户外人体数据测量对测量载平台的需求,通过研究人因导向产品的映射分析方法和设计模型,制订户外测量舱的人因设计准则、映射分析规则,以及分析方法和设计模型,并以实际户外人体数据任务案例为例,进行户外测量舱的具体分析、设计和应用。通过与室内测量平台、临时载平台进行比较评价,人因导向映射分析设计可支持户外测量舱满足户外高效、经济的人体测量任务,具有良好的户外环境适应性、人员舒适性和设备安全性。
师国伟王中天郑学文李林杉王聪王兴伟
Investigating the causal associations between five anthropometric indicators and nonalcoholic fatty liver disease:Mendelian randomization study
2024年
BACKGROUND Although the etiology of nonalcoholic fatty liver disease(NAFLD)has not been thoroughly understood,the emerging roles of anthropometric indicators in assessing and predicting the risk of NAFLD have been highlighted by accumulating evidence.AIM To evaluate the causal relationships between five anthropometric indicators and NAFLD employing Mendelian randomization(MR)design.METHODS The Anthropometric Consortium provided genetic exposure data for five anthropometric indicators,including hip circumference(HC),waist circumference(WC),waist-to-hip ratio(WHR),body mass index(BMI),and body fat percentage(BF).Genetic outcome data for NAFLD were obtained from the United Kingdom Biobank and FinnGen Consortium.Genome-wide significant single nucleotide polymorphisms were chosen as instrumental variables.Univariable MR(UVMR)and multivariable MR(MVMR)designs with analytical approaches,including inverse variance weighted(IVW),MR-Egger,weighted median(WM),and weighted mode methods,were used to assess the causal relationships between anthropometric indicators and NAFLD.RESULTS Causal relationships were revealed by UVMR,indicating that a higher risk of NAFLD was associated with a perunit increase in WC[IVW:odds ratio(OR)=2.67,95%CI:1.42-5.02,P=2.25×10^(−3)],and BF was causally associated with an increased risk of NAFLD(WM:OR=2.23,95%CI:1.07-4.66,P=0.033).The presence of causal effects of WC on the decreased risk of NAFLD was supported by MVMR after adjusting for BMI and smoking.However,no causal association between BF and NAFLD was observed.In addition,other causal relationships of HC,WHR(BMI adjusted),and BMI with the risk of NAFLD were not retained after FDR correction.CONCLUSION This study establishes a causal relationship,indicating that an increase in WC is associated with a higher risk of NAFLD.This demonstrates that a suitable decrease in WC is advantageous for preventing NAFLD.
Xian-Pei XiaoYong-Jun DaiYu ZhangMeng YangJian XieGuo ChenZheng-Jun Yang
Causal association of obesity-related anthropometric traits with myopia and the mediating role of educational attainment:a Mendelian randomization study
2024年
AIM:To study the causal relationship between obesityrelated anthropometric traits and myopia and the mediating role of educational attainment(EA).METHODS:Univariable Mendelian randomization(UVMR)was performed to evaluate the causal association between body mass index(BMI),height,waist-hip ratio(WHR,adjusted for BMI),and mean spherical equivalent(MSE).BMI was divided into fat and fat-free mass and included in multivariable Mendelian randomization(MVMR)to explore the roles of different BMI components in the causal relationship between BMI and MSE.A mediation analysis based on two-step Mendelian randomization(MR)was carried out.Specifically,UVMR was conducted to estimate the causal effect of BMI on EA.The direct effect of EA on MSE was estimated from MVMR.The mediation effect of EA in the BMI-EA-MSE model was calculated by the product of coefficients method.Expression quantitative trait loci(eQTL)-MR,reverse MR,and Linkage Disequilibrium Score Regression(LDSC)were performed to assess the robustness.RESULTS:Genetically predicted higher BMI had a positive total effect on MSE(βIVW=0.26 D,95%CI=0.14 to 0.37 D,P<0.001),whereas there was no significant association between height,WHR,and MSE.Fat mass was found to play a significant role in the effect of body mass on MSE(βIVW=0.50 D,95%CI=0.21 to 0.78 D,P=0.001),but there was no significant association between fat-free mass and MSE.The causal effect of BMI on EA was-0.14(95%CI=-0.16 to-0.11,P<0.001),and the direct effect of EA on MSE was-0.63 D(95%CI=-0.81 to-0.44 D,P<0.001).The mediating effect of EA in the BMI-EA-MSE model was 0.09 D(95%CI=0.06 to 0.12 D),with a mediation proportion of 33%(95%CI=22.1%to 44.6%).No reverse causal associations were detected except for BMI on EA.The results of eQTL-MR and LDSC were consistent with each MR analysis.CONCLUSION:Genetically predicted higher BMI decreases the degree of myopia with a 33%mediation proportion by EA,and fat mass provides a dominant protective role in body mass-myopia.As a supplement to previous observational studies
Yi LuCan-Can ZhangRun-Ting MaYuan-Jing LiWen-Ping LiDie-Wen-Jie HuLian-Hong Zhou
关键词:MYOPIA
Draft of an Anthropometric Reference System for Full-Term Cameroonian Newborns: Prospective Study with Analytical Aim in the Maternity Wards of Douala
2024年
Introduction: Anthropometry applied to newborns is a reliable indicator of the quality of fetal growth. The latter is influenced by genetic, racial and nutritional factors varying from one population to another, explaining why a standard cannot be applied to all populations. Research question: should the Caucasian frame of reference be dogmatically applied in our African context? Multicenter studies are therefore necessary;hence the interest of this work, the main objective of which was to describe the anthropometric profile of full-term newborns in the city of Douala. Methodology: We carried out a cross-sectional study with an analytical aim and prospective data collection in the maternity wards of the Douala General Hospital, Laquintinie Hospital, District hospitals of Deido, Nylon and Bonassama over a period of 4 months (January to April 2020). We were interested in any newborn, born alive, vaginally or by cesarean section, seen in the first 24 hours from a full-term single-fetal pregnancy whose mother had given consent. We excluded newborns whose term was unclear and those with congenital malformations or signs of embryo-foetopathy. Data collection was done using structured and pre-tested survey sheets. The study variables were obstetric and anthropometric. Statistical analyzes were carried out with CS Pro 7.3 and SPSS version 25.0 software. The Student, Chi-square and Fischer tests were used to compare the means of the variables, the percentages with a significance threshold P value Results: During the study period, 305 full-term newborns were included, divided into 172 boys and 133 girls. The average anthropometric parameters of the full-term newborn in the city of Douala were: average weight: 3305 grams, average height: 49.8 centimeters, average head circumference: 34.6 centimeters, average upper arm circumference: 11.3 centimeters, circumference average thoracic: 32.8 centimeters. The percentile distribution showed a 10th percentile at 2656 grams and a 90th percentile at 3966 grams for weight defining the
Henri EssomeCharlotte Epossè EkoubeFulbert Mangala NkweleRita Carole Mbono BetokoIrène Cyrielle Edjoa MboeMichel Roger EkonoAlphonse Ngalame NyongRobert TchounzouIngrid Doriane Ofakem IlickHassanatou IyawaMoustapha BilkissouAstrid Ndolo KondoJunie Ngaha YaneuMarga Vanina Ngono AkamGervais Mounchikpou NgouhouoGrâce Tocki ToutouNelly NoubiValère Mve KohThéophile Nana Njamen
关键词:ANTHROPOMETRY
Efficacy of a Diabetes Specific Nutrition Supplement on Glycemic, Anthropometric, Dietary and Gut Health Markers in Adults with Type 2 Diabetes: An RCT
2024年
With increasing incidence of diabetes, use of diabetes specific nutrition supplements (DSNS) is common for better management of the disease. To study effect of 12-week DSNS supplementation on glycemic markers, anthropometry, lipid profile, SCFAs, and gut microbiome in individuals with diabetes. Markers studied were glycemic [Fasting Blood Glucose (FBG), Post Prandial Glucose (PPG), HbA1c, Incremental Area under curve (iAUC), Mean Amplitude of Glycemic Excursions (MAGE), Time in/above Range (TIR/TAR)], anthropometry [weight, Body Mass Index (BMI), waist circumference (WC)], lipid profile, diet and gut health [plasma short chain fatty acids (SCFAs)]. N = 210 adults were randomized to receive either DSNS with standard care (DSNS + SC;n = 105) or standard care alone (SC alone;n = 105). After 12 weeks, significant differences between DSNS + SC versus SC alone was observed in FBG [−3 ± 6 vs 14 ± 6 mg/dl;p = 0.03], PPG [−35 ± 9 vs −3 ± 9 mg/dl;p = 0.01], weight [−0.6 ± 0.1 vs 0.2 ± 0.1 kg;p = 0.0001], BMI [−0.3 ± 0.1 vs 0.1 ± 0.1 kg/m2;p = 0.0001] and WC [−0.3 ± 0.2 vs 0.2 ± 0.2 cm;p = 0.01]. HbA1C and low-density lipoprotein (LDL) were significantly reduced in DSNS + SC [−0.2 ± 0.9;p = 0.04 and −5 mg/dl;p = 0.03] respectively with no change in control. Continuous Glucose Monitoring (CGM) reported significant differences between DSNS + SC versus SC alone for mean glucose [−12 ± 65 vs 28 ± 93 mg/dl;p < 0.01], TAR 180 [−9 ± 42 vs 7 ± 45 mg/dl;p = 0.04], TAR 250 [−3 ± 27 vs 9 ± 38 mg/dl;p = 0.05], iAUC [−192 (1.1) vs −48 (1.1) mg/dl;p = 0.03]. MAGE was significantly reduced for both DSNS + SC (−19 ± 67;p < 0.001) and SC alone (−8 ± 70;p = 0.04), with reduction being more pronounced for DSNS + SC. DSNS + SC reported a decrease in carbohydrate energy % [−9.4 (−11.3, −7.6) %;p < 0.0001] and amount [−47.4 (−67.1, −27.7) g;p < 0.0001], increased dietary fiber [9.5 (7.2, 11.8) g;p < 0.0001] and protein energy % [0.9 (0.5, 1.3) %;p < 0.0001] versus SC alone. DSNS + SC r
Deepti KhannaHema S. GopalanKuzhandaivelu AbiramiVasudevan SudhaRajagopal GayatriKejal Joshi-ReddyJaladhi BhattRaman Ganesh JeevanKarthikeyan ParkaviVadivel DeepikaManoj PareekRanjit Mohan AnjanaViswanathan Mohan
关键词:DIABETES
基于人体测量参数的个性化HRTF建模
2024年
头相关传输函数(Head Related Transfer Function, HRTF)在空间音频渲染中具有关键作用,能够显著提升个体的听觉体验。然而,要实现最佳的听觉效果,HRTF必须与受试者的解剖特征相符。为了达到这一目标,采用了一种基于人体测量特征的方法来估算个体化HRTF,特别地,扩展了耳廓的测量参数,并考虑了常被忽略的耳廓腔室对HRTF的影响。通过主动形状模型(Active Shape Models, ASM),自动从特定耳廓的标记点提取耳廓测量参数。接着,使用轻量级梯度提升机(Light Gradient Boosting Machine, LightGBM)模型,根据提取的耳廓测量参数及头部测量参数,预测个体在中垂面上的HRTF幅度。评估结果显示,所提取的耳廓特征能够显著提升HRTF个性化的客观性能指标。
魏永健周静雷
关键词:ASM
民航飞行员12项人体测量学指标的聚类分析及验证
2024年
目的聚类分析民航飞行员12项人体测量学指标,探索空腹胰岛素(fasting insulin,FINS)与民航飞行员飞行时间及肥胖程度的关系。方法选取2021年9月—2022年2月在民航上海医院进行体格检查和辅助检查的1250名在职男性飞行员,使用Inbody人体成分分析仪测定其身高、体质量、腰围、臀围及体脂率等指标,通过问卷调查了解其执飞机型及2021年飞行时间数据。使用12项人体测量学指标通过主成分分析法进行聚类分析,并进一步以多元线性回归法2种模型比较分析FINS与民航飞行员年飞行时间及人体测量学指标的关系,为本次人体测量学指标聚类分析进行验证。结果对12项人体测量学指标经适宜性检验后行因子分析,以主成分法提取3个公因子(脂质堆积指数、腰围甘油三酯指数和内脏脂肪指数),累计方差贡献率为95.29%,进一步采用线性回归法计算出标准化得分系数,最后采用多元线性回归法分析得出FINS与年飞行时间及3个公因子(中心型肥胖因子、全身型肥胖因子、内脏型肥胖因子)均有关(3个公因子的偏回归系数分别为12.37、8.90、6.78,P均<0.001),且中心型肥胖程度对空腹胰岛素的升高有最大的贡献作用。结论中心型肥胖因子、全身型肥胖因子及内脏型肥胖因子与空腹胰岛素升高均具有相关性,且中心型肥胖公因子贡献最大,提示人体测量学指标具有临床预测价值。
王芳王妍喻筱维杨金凤戴俊明傅力
关键词:人体测量指标主成分分析空腹胰岛素民航飞行员
三酰甘油-葡萄糖指数及其联合人体测量学指标与心血管疾病相关性的研究进展被引量:2
2024年
近年研究发现,三酰甘油-葡萄糖(TyG)指数是早期评估胰岛素抵抗简易灵敏的替代指标,在心血管疾病的风险预测、危险分层及预后评估方面有重要意义。一些学者将TyG与人体测量学指标相结合,发现可更好地预测心血管疾病风险。故本文就TyG及其联合人体测量学相关指标在高血压、冠心病等心血管疾病中的应用价值及研究进展进行综述。
卢彦娜梁超唐强
关键词:心血管疾病人体测量学指标
2019年山东省人体测量指标对代谢综合征患病风险联合预测价值
2024年
目的评价多种人体测量指标及其组合对普通人群代谢综合征(MetS)患病风险的预测价值。方法2019年4月通过四阶段整群抽样、统一编制的问卷和体格测量对山东省3477名18~69岁常住居民的人体测量指标水平与MetS患病状况进行调查,并分析各人体测量指标对MetS患病风险的独立及联合预测价值。结果MetS患者的各项人体测量指标[体质量指数(BMI)、腰围(WC)、腰臀比(WHR)、腰围身高比(WtHR)、锥度指数(CI)、体形指数(ABSI)、身体圆度指数(BRI)、腹部体积指数(AVI)]明显高于非MetS患者人群(P<0.001)。logistic回归分析模型2结果表明,男性WC的Z-分数比值比(OR)最大,为3.73[95%置信区间(CI):2.80~4.97];女性WtHR的Z-分数OR值最大,为2.70(95%CI:2.13~3.42)。受试者工作特征曲线(ROC)分析显示,男性WC和AVI的ROC曲线下面积(AUC)最大,均为0.83(95%CI:0.80~0.85);女性WC、WtHR、BRI和AVI的AUC值均为0.82。依据最佳截断值将WC、WtHR、BRI和AVI划分高低水平,高水平WC与高水平WtHR、BRI或AVI联合时OR值最大;WC与AVI的高水平组合的灵敏度、特异度和阳性预测值(PPV)与WC单独预测时相近(男性:灵敏度为91.44%、特异度为64.88%、PPV为44.95%;女性:灵敏度为90.85%、特异度为63.80%、PPV为32.58%);男性WC与WtHR或BRI的高水平组合的特异度和PPV明显提高,灵敏度则显著降低(高WC-高WtHR:灵敏度为69.28%、特异度为79.78%、PPV为51.92%;高WC-高BRI:灵敏度为71.23%、特异度为78.73%、PPV为51.23%);女性呈现相同趋势,但增减幅度较小。结论WtHR或BRI与WC组合可改善预测代谢综合征患病风险的特异度和阳性预测值,在慢性病重点人群管理过程中,可应用于MetS患病高危人群的筛查和预测。
杨根招曹青张丙银唐俊利董静任杰徐春晓鹿子龙刘丹茹郭晓雷
关键词:人体测量指标代谢综合征

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许志成
作品数:22被引量:24H指数:3
供职机构:上海交通大学医学院附属第九人民医院
研究主题:先天性小耳畸形 肋软骨 血管平滑肌细胞 毛囊干细胞 全耳再造