Background: Cervical Intraepithelial neoplasia treatments have become essential interventions to manage cervical lesions. Majority of the recipients of these treatments are women within the reproductive age group, who according to literature may be at risk of adverse pregnancy outcomes. This pilot study is part of a study investigating adverse pregnancy outcomes among women who received Cryotherapy, Thermal ablation and Loop Electrosurgical Excision Procedure compared to the untreated women in Zambia. Materials and Methods: This descriptive study analyzed records of 886 (n = 443 treated and n = 443 untreated) women aged 15 - 49 years. The women were either screened with Visual Inspection with Acetic Acid or treated for Cervical Intraepithelial neoplasia at the Adult Infectious Disease Centre between January 2010 and December 2020. Women meeting the criteria were identified using the Visual Inspection with Acetic Acid screening records and telephone interviews to obtain the adverse pregnancy outcome experienced. Data were analysed using STATA version 16 to determine the prevalence and obtain frequency distribution of outcomes of interest. Univariate and multivariable binary logistic regression estimated odds of adverse pregnancy outcomes across the three treatments. Results: The respondents were aged 15 to 49 years. Adverse pregnancy outcomes were observed to be more prevalent in the treatment group (18.5%) compared to the untreated group (5.4%). Normal pregnancy outcomes were lower in the treated (46.3%;n = 443) than the untreated (53.7%;n = 443). The treated group accounted for the majority of abortions (85.2%), prolonged labour (85.7%) and low birth weight (80%), whereas, the untreated accounted for the majority of still births (72.7%). Women treated with cryotherapy (aOR = 2.43, 95% CI = 1.32 - 4.49, p = 0.004), thermal ablation (aOR = 6.37, 95% CI = 0.99 - 41.2, p = 0.052) and Loop Electrosurgical Excision Procedure (aOR = 9.67, 95% CI = 2.17 - 43.1, p = 0.003) had two-, six- and ten-times higher odds of adve
Victoria Mwiinga-KalusopaJohanna E. MareeConcepta KwaleyelaPatricia Katowa-Mukwato
目的探究冰水冷疗在关节手术患者术后行关节锻炼镇痛中的有效性。方法选取钦州市第一人民医院行关节置换手术及关节镜手术的400例患者,随机数表法将其分为试验组和对照组,每组200例。2组进行关节锻炼后,对照组给予固体冰袋冷疗治疗;试验组行康玛士(Kindman)布冰袋冰水冷疗。比较2组患者术后疼痛程度[数字评分法(NPS)]、肿胀程度、关节活动度及并发症,并分析患者生活质量(SF-36量表)及对护理满意度。结果与对照组比较,试验组8、24、48 h NRS评分依次降低(P<0.05),且不同时间比较具有交互效应(P<0.05)。与对照组比较,试验组在8、24、48 h的肿胀程度降低效果更明显(P<0.05)。与对照组比较,试验组关节活动度优良率更高(P<0.05)。试验组并发症发生率低于对照组(P<0.05)。与对照组比较,试验组术后3、5 d SF-16评分均显著升高(P<0.05)。试验组护理满意度高于对照组(P<0.05)。结论康玛士布冰袋冰水冷疗在关节手术患者术后行关节锻炼中可明显降低患者疼痛程度,改善关节活动度,提高生活质量。