In the present experiment, Pavlovian fear conditioning was adopted to study the effects of different early rearing environments on fear conditioning in adult rats. Weaned rats were reared in three manipulable environments （enriched, social and isolated conditions）. After 8 weeks, fear conditioning （characterized by percentage of freezing） was observed and analyzed, and rats＇ weight, locomoter activity and foot-shock sensitivity were operated too. The results showed that： （1） Compared with control group, the level of conditioned fear was significantly increased in enriched group, but significantly decreased in isolated group; （2） Enriched and isolated conditions influenced rat＇s weight significantly; （3） Different rearing conditions have no effect on locomoter activity and foot-shock sensitivity. These results indicated that early enriched condition could improve the tone-evoked fear conditioning response, while isolated condition impaired the response.
＜正＞Previous studies have shown that REM sleep deprivation（RSD） exerts a detrimental effect on some memory task...
Juan Fu~1 Peng Li~2 Xinping Ouyang~1 Shaowen Tian~(1,*) and Bi Hu~(1,*) (1.College of Medicine,Nanhua University,Hengyang,Hunan,421001,P.R China 2.College of Life Science and Technology,Nanhua University,Hengyang,Hunan,421001,P.R China)
＜正＞Previous studies have shown that opioids transmission plays an important role in learning and memory.Howeve...
Chaoliang Gu~1 Peng Li~2 Bi Hu~2 Xinping Ouyang~1 Shaowen Tian~(1,*) (1.College of Medicine,Nanhua University,Hengyang,Hunan,421001,P.R China 2.College of Life Science and Technology,Nanhua University,Hengyang,Hunan,421001,P.R China)
