Octacosanol is purified by agitated short-path distillation (SPD). Effects of evaporation temperature,number of SPD steps in series and other distillation method on the octacosanol recovery and decomposition are studied. Although the experimental results indicate some decomposition when the mixture of higher primary aliphatic alcohols is distillated by SPD, SPD is still an effective method to purify octacosanol. It is concluded that evaporation temperature affects greatly on the purity and recovery of octacosanol.
Pharmaceutical oil is obtained from peanut oil by wiped film short path distiller(SPD).The concentration ofeffective unsaturated fatty acids in the pharmaceutical oil is more than five percentages,the evaporation rate is more than25%.The experiment results indicate that the optimum technology parameters for wiped film SPD are that feed flow rateis 131 mL/h,operation pressure is 0.1 Pa,agitation speed is 140 rmp,temperature of feed is 190℃and the best evapo-ration is 260℃.
