In the field of anthropology, the uniparerttally inherited Y chromosome has long been used to trace the paternal lineage of the populations and to understand differences in migration and population genetics between males and females, with additional advantages of small effective population size, suf- ficient markers, and population-specific haplotype distribution (Jobling and Tyler-Smith, 1995; Jin and Su, 2000; Underhill et al., 2000). Many such population studies have rested on the assumption that all the Y chromosome markers in the non- recombination regions are selectively neutral (Jobling and Tyler-Smith, 2003).