Henan Province is an important grain production base, whose stable production is related to the economic development and social stability significantly. To summarize the primary factors of grain producing, we used grey correlation analysis method to analyze 10 correlative factors such as grain yield, grain yield per unit area, effective irrigated area, rural employed persons, grain planting area, consumption of chemical fertilizer in 25 years. The results showed order of synthetic degree of incidence: effective irrigated area>rural electricity consumption>consumption of chemical fertilizer>disaster crop area>grain yield per unit of area>total power of agricultural machinery>afflicted crop area>grain planting area>number of the rural employed persons. Finally, according to synthetic degree of incidence between influential factors and total grain output respectively, a series of measures and the suggestions was proposed for grain production in Henan Province, which will also provide the scientific basis and help for the government correct decision-making.