Green fluorescent protein（GFP） plasmid was caged by 8-bromo-7-hydroxyquinolinyl chromophore（BHQ） for controlling its expression with exact spatiotemporal resolution.In vitro and in vivo experiments clearly verified that,comparing with Bhc caging, the expression level of caged GFP plasmid was dramatically decreased and then efficiently restored after subsequent photolysis.
A novel chemosensor 1 （CS1） bearing one coumarin and two carbodithioate groups was synthesized and its fluorescent sensing behavior toward metal ions was investigated. Ag^＋ addition to a CH3COCH3/H2O （3：7, v：v） solution of CS1 gave a significantly quenched fluorescence. Other ions including Pb^2＋, Zn^2＋, Cu^2＋, Ca^2＋, Cd^2＋, Co^2＋, Mg^2＋, Mn^2＋, Hg^2＋, Ag^＋, Ni^2＋ induced no or much smaller spectral changes. This constitutes an ON-OFF Ag^＋-selective fluorescent chemosensor.
Mao Xiang Wang Xiang Ming Meng Man Zhou Zhu Qing Xiang Guo
A novel fluorescent Zn^2＋ probe based on 6-methoxyquinolin was synthesized in four steps from inexpensive starting materials. It exhibits very strong fluorescence responses and has a remarkably high selectivity to Zn^2＋ than other physiological relevant metal ions. This new compound could be used as low-priced yet high-quality Zn^2＋ probe.
Hua Yang ZhaoYi Ming LiTian Jun GongQing Xiang Guo
