In this paper, we present a distributed multi-level cache system based on cloud storage, which is aimed at the low access efficiency of small spatio-temporal data files in information service system of Smart City. Taking classification attribute of small spatio-temporal data files in Smart City as the basis of cache content selection, the cache system adopts different cache pool management strategies in different levels of cache. The results of experiment in prototype system indicate that multi-level cache in this paper effectively increases the access bandwidth of small spatio-temporal files in Smart City and greatly improves service quality of multiple concurrent access in system.