Objective The CH9417 Anti epilepsy Instrument was designed according to chaotic theory. The goal of this study was to evaluate its therapeutic effect of anti epilepsy.Methods The epilepsy animal model was established by using Bemagle in rats. Two treatment groups and one control group were used, 15 Spradue Dawley rats for each group. All animals were treated with CH9417 Anti epilepsy Instrument for 20 min each time twice a day for five days as one course. The behavioral changes of epilepsy onset were observed and the syndrome was divided into 0 5 stage. The total therapeutic duration was three courses.Results The results suggested that the latency of Bemagle induced epilepsy episode was significantly prolonged in both 0.1 mA and 0.05 mA treatment groups. In the 3rd course, the latent time was (1.70±0.9) min for control group and (3 97±2 32) min, (8 75±3.58) min for groups of 0.05 mA and 0.1 mA treatment, respectively. The latent time of epilepsy wave in EEG was also prolonged. \;
目的 观察两个从国产特有蝎种东亚钳蝎 (Bm K)分离的毒素多肽 Bm K 、Bm K 对昆虫中枢神经自发放动作电位的影响。方法 采用蜚蠊中枢神经自发放胞外记录方法。结果 Bm K 对蜚蠊中枢神经自发放动作电位有双相作用 ,先抑制后兴奋 ,其抑制作用是可逆的。Bm K 对蜚蠊中枢神经自发放动作电位有抑制作用 ,其抑制作用不是可逆的。结论 提示 Bm K 是神经抑制性成分与兴奋性成分的混合物 ,Bm K 中只有抑制成分。推测
