Seismic design should quantitatively evaluate and control the risk of earthquake-induced collapse that a building structure may experience during its design service life. This requires taking into consideration both the collapse resistant capacity of the building and the earthquake ground motion demand. The fundamental concept of uniform-risk-targeted seismic design and its relevant assessment process are presented in this paper. The risks of earthquake-induced collapse for buildings located in three seismic regions with the same prescribed seismic fortification intensity but different actual seismic hazards are analyzed to il- lustrate the engineering significance of uniform-risk-targeted seismic design. The results show that with China's current seis- mic design method, the risk of earthquake-induced collapse of buildings varies greatly from site to site. Additional research is needed to further develop and implement the uniform-risk-targeted seismic design aoDroach oronnsed in thi~ nnner