您的位置: 专家智库 > >

国家自然科学基金(81202846)

作品数:7 被引量:33H指数:4
相关作者:宇文亚韩学杰杨伟刘大胜吕爱平更多>>
相关机构:中国中医科学院中国中医科学院西苑医院陕西中医药大学更多>>
发文基金:国家自然科学基金中国中医科学院自主选题项目更多>>
相关领域:医药卫生更多>>

文献类型

  • 6篇中文期刊文章

领域

  • 6篇医药卫生

主题

  • 4篇血压
  • 4篇高血压
  • 3篇痰瘀
  • 2篇痰瘀同治
  • 2篇顽固性
  • 2篇顽固性高血压
  • 2篇高血压病
  • 1篇治法
  • 1篇治疗方药
  • 1篇痰瘀互结
  • 1篇痰瘀互结证
  • 1篇痰瘀同治法
  • 1篇同治法
  • 1篇中医
  • 1篇中医临床
  • 1篇中医临床实践
  • 1篇中医临床实践...
  • 1篇中医药
  • 1篇疗效
  • 1篇疗效评价

机构

  • 4篇中国中医科学...
  • 2篇中国中医科学...
  • 1篇陕西中医药大...
  • 1篇香港浸会大学

作者

  • 4篇韩学杰
  • 4篇宇文亚
  • 2篇吕爱平
  • 2篇杨伟
  • 2篇刘大胜
  • 1篇翁维良
  • 1篇谢雁鸣
  • 1篇刘兴方
  • 1篇赵学尧
  • 1篇刘玉祁
  • 1篇沈绍功
  • 1篇沈舒文
  • 1篇徐建龙

传媒

  • 2篇中华中医药杂...
  • 1篇中医杂志
  • 1篇Chines...
  • 1篇中华中医药学...
  • 1篇Journa...

年份

  • 2篇2018
  • 1篇2015
  • 2篇2014
  • 1篇2013
7 条 记 录,以下是 1-6
排序方式:
痰瘀同治法治疗顽固性高血压真实世界疗效评价的思路与方法被引量:7
2013年
临床疗效评价实际上是干预措施与临床结局间因果关系的判断。痰瘀同治法治疗顽固性高血压在临床真实环境下的疗效优势是客观存在的事实,但由于缺乏科学的疗效评价方法,使其疗效很难得到行业认可。据此我们在明确痰瘀同治法治疗顽固性高血压有效性的基础上,开展真实世界研究中因果推断的方法研究,以期为该治法的疗效证据奠定方法学基础。
宇文亚韩学杰谢雁鸣刘玉祁沈绍功吕爱平
关键词:痰瘀同治顽固性高血压疗效评价
Appraisal of the Quality and Contents of Clinical Practice Guidelines for Hypertension Management in Chinese Medicine: A Systematic Review被引量:8
2018年
Objective: To evaluate the quality and consistency of recommendations in the clinical practice guidelines(CPGs) for hypertension in Chinese medicine(CM). Methods: CM CPGs were identified from 5 electronic databases and hand searches through related handbooks published from January 1990 to December 2013. Three reviewers independently appraised the CPGs based on the Appraisal of Guidelines for Research and Evaluation(AGREE Ⅱ) instrument, and compared the CPGs' recommendations on CM syndrome pattern classification and treatment. Results: Five CM CPGs for hypertension were included. The quality score of the evidence-based(EB) guideline was higher than those of the consensus-based with no explicit consideration of evidence-based(CB-EB) and the consensus-based(CB) guidelines. Three out of five patterns in the CPGs were recommended by the EB guideline. Tianma Gouteng Formula(天麻钩藤复方) in the EB guideline was recommended mostly for hypertension patients with pattern of ascendant hyperactivity of Gan(Liver)-yang and pattern of yin deficiency with yang hyperactivity in the CPGs. Acupuncture and massage were recommended for Grade Ⅰ and Grade Ⅱ hypertension with severe symptoms weakening the quality of life in the EB guideline. For Grade Ⅰ and Grade Ⅱ hypertension, CM could be used alone, while for Grade Ⅲ hypertension, they should be used in combination with Western medicines. Conclusion: The quality of EB guideline was higher than those of CB and CB-EB CPGs in CM for hypertension and CM should be prescribed alone or combined with Western medicines based on the grade of hypertension.
YUWEN YaHAN Xue-jieWENG Wei-liangZHAO Xue-yaoLIU Yu-qiLI Wei-qiangLIU Da-shengWANG Yan-pingLU Ai-ping
关键词:HYPERTENSION
痰瘀同治高血压病的最佳干预时间和有效人群研究被引量:1
2014年
目的:研究痰瘀同治1、2级高血压病的最佳干预时间和有效人群。方法:将86例1、2级高血压病患者随机分为试验组38例,对照组48例。试验组采用中医药痰瘀同治,对照组服用降压西药,两组均治疗12周。分别于治疗前、治疗2、4、8、12周观察血压、症状积分、不良事件。结果:两组治疗2、4、8、12周改善血压总有效率比较均无统计学差异,试验组在治疗4、12周总有效率最高;两组治疗2、4、8、12周改善头晕、头如裹、身重困倦均无显著差异。两组在治疗12周,试验组改善心悸、胸闷、恶心优于对照组(P<0.05)。结论:本研究初步表明,痰瘀同治1、2级高血压病的最佳干预时间是12周,有效人群为心悸、胸闷、恶心的1、2级高血压病患者。
宇文亚韩学杰杨伟刘兴方刘大胜吕爱平
关键词:痰瘀同治高血压病
基于AGREEⅡ工具的高血压病中医临床实践指南评价被引量:8
2014年
目的:采用AGREEⅡ工具评价我国已经发布的高血压病中医临床实践指南的质量。方法:采用手工检索与网络检索相结合的方法,检索国内已经公开发布的高血压病中医临床实践指南。采用AGREEⅡ工具进行评价,每个指南由3名评价者进行评价。分别分析每个指南的范围与目的、参与人员、制定的严谨性、清晰性与可读性、应用性、编辑独立性,最后进行指南的全面评估。结果:共纳入6个指南,评价结果表明,高血压病中医临床实践指南的清晰性与可读性质量最高,平均得分为60.2%;其次为编辑的独立性,平均得分52.9%;参与人员平均得分50.0%;制定的严谨性平均得分47.1%;范围和目的平均得分42.6%;应用性质量最低,平均得分37.8%。全面评估显示,强烈推荐使用的指南有2个,推荐(补充或改进)的指南有2个,2个指南不能确定是否推荐使用。结论:高血压病中医临床实践指南的应用性很低,在以后的指南研制中,要注重指南应用性质量的提高。
刘大胜赵学尧宇文亚韩学杰徐建龙
关键词:临床实践指南中医药高血压病
顽固性高血压痰瘀互结证治疗方药方案精准化的思路和方法被引量:6
2018年
中医走精准发展路是改变自身弱势学科地位的必然趋势,真实世界与大数据技术能解决辨证论治存在的客观证据与精细化、量化不足的难题,据此本研究在既往肯定痰瘀辨治顽固性高血压(Resistant Hypertension, RH)有效的基础上,提出了基于真实世界和大数据技术的RH痰瘀互结精准方药方案的思路和方法,为解决辨证论治中方药方案精准的共性技术提供方法学上新发现。
宇文亚沈舒文杨伟韩学杰翁维良
关键词:顽固性高血压痰瘀互结证
The add-on effect of a Chinese herbal formula for patients with resistant hypertension: study protocol for a pilot cohort study被引量:2
2015年
BACKGROUND: Despite a recent American Heart Association (AHA) consensus statement emphasizing the importance of resistant hypertension (RH), its control is still a challenge for conventional medicine. The Chinese herbal formula, Qutan Huayu Fang, has been used effectively to assist antihypertensive agents in blood pressure control, but its effect for RH patients is still unclear. This pilot study aims to explore the effects of taking the formula in addition to antihypertensive medication in the management of RH. METHODS/DESIGN: A prospective cohort study will be conducted in two first-class hospitals of traditional Chinese medicine (TCM). Eligible RH patients will be classified as the experimental group (n = 100) and the control group (n = 100) based on the interventions they receive. Participants taking antihypertensive agents and the Chinese herbal formula will be in the experimental group and those taking antihypertensive agents alone will be in the control group. The whole study will last 24 weeks, including an 8-week observation and follow-up at 24 weeks. The primary outcomes, assessed against patient baseline conditions, will be the reduction of systolic blood pressure and diastolic blood pressure as well as changes in TCM symptoms and signs. These outcomes will be assessed at weeks 2, 4, 6, and 8. The reductions of blood pressure will also be assessed at week 24. Cardiac events and mortality rate will be secondary outcomes and will be assessed at weeks 8 and 24. Any adverse reactions will be recorded during the study. The causal inference method will be used to assess the effectiveness of the inclusion of TCM herbal medicine in the management of patients with RH. DISCUSSION: This study will determine whether the Chinese herbal formula is helpful for RH patients treated with antihypertensive agents and the findings will provide a basis for further confirmatory studies TRIAL REGISTRATION NUMBER: ClinicalTria/s.gov Identifier NCT01904695
Ya YuwenYu-qi LiuYan-ping WangJin-gang DaiDa-sheng LiuYue-xi WangXue-jie Han
共1页<1>
聚类工具0