[Objective] This study was conducted to provide and promote high-yield,high-sugar, high-lodging resistance cane varieties and change the situation of singleness of sugarcane variety in Guangxi. [Method] The variety, Guitang 04-1001（Guitang 42）, a progeny of the cross ROC22 ×Guitang 92-66, was bred and evaluated in the aspects of morphological characteristics and production characteristics through the breeding program of a five-nursery-system protocol by both regional and production trials. [Results] Under many years of experiments, Guitang 42 was shown with high stalk, medium to large stalk diameter, easy stripping, good germination, medium tillering ability, and more population of millable stalks; and high resistance to mosaic and pokkah boeng, medium resistance to smut, high drought tolerance, and good ratooning ability. During the five-nursery-system procedure, the average of cane and sugar yield was 95.06-108.87 t/hm^2 and 15.11-16.85 t/hm^2, which were higher than CK by 11.3%-14.1% and 16.0%-18.9%, respectively. In the regional trial in 2011 and 2012, the achieved cane yield of 101.7 t/hm^2, sugar yield of 15.03 t/hm^2 and sucrose contents of 14.46% were higher than CK by 9.26%, 14.45% and0.66%, respectively. In the production trial in 2012, the average cane yield was88.62 t/hm^2, which was higher than ROC22 by 7.9%. Guitang 42 was approved by Guangxi Crop Variety Approval Committee in 2013 and elected to Guangxi Top 10 sugarcane commercial variety in 2014. [Conclusion] Guitang 42 has the characteristics of early maturity, high yield, high sugar content, good ratooning ability, and high resistance to lodging（i.e., good comprehensive traits）, and could be popularized in south sugarcane regions in China.
