Have you ever heard of OZAI?It is a blind box product of Heyone,which was first launched in May 2022.In June this year,the two-year-old OZAI launched a new model featuring the theme“Spring Garden Party”,which was snapped up instantly.A netizen who participated in the snapping-up of these during the official live broadcast posted that there were 20,000 people online at that time,and the link showed“sold out”only one second after it went online.Offline sales were even more popular.Two days before the sale,consumers lined up at the TOPTOY store.How does a blind box with unknown contents become a best seller?
目的分析维持性透析并发继发性甲状旁腺功能亢进(SHPT)患者甲状旁腺切除术(PTX)术后发生骨饥饿综合征(HBS)的影响因素。方法41例维持性透析并发SHPT患者行PTX,其中24例术后发生HBS(HBS组),17例未发生HBS(非HBS组)。收集患者临床资料,采用多因素logistic回归分析PTX术后发生HBS的影响因素,绘制ROC曲线评价骨代谢指标对PTX术后发生HBS的预测价值。结果与非HBS组相比,HBS组血液透析比例、术前3 d碱性磷酸酶(ALP)、抗酒石酸酸性磷酸酶5b(TRACP-5b)和术后1周ALP、骨钙素水平升高,而术前3 d血钙、全段甲状旁腺激素(iPTH)、25-羟维生素D[25-(OH)D]、骨钙素和术后1周血钙、iPTH、25-(OH)D水平降低(P<0.05)。术前3 d ALP水平升高是维持性透析并发SHPT患者行PTX术后发生HBS的独立危险因素(P<0.05),而术前3 d 25-(OH)D水平升高是其独立保护因素(P<0.05)。术前3 d ALP与25-(OH)D联合预测PTX术后发生HBS的AUC高于术前3 d ALP和25-(OH)D单独检测(0.934 vs.0.811和0.798)(P<0.05)。结论术前25-(OH)D和ALP水平是维持性透析并发SHPT患者PTX术后发生HBS的影响因素,两者联合检测对其具有较高的预测价值。